RhoA effector mutants reveal distinct effector pathways for cytoskeletal reorganization, SRF activation and transformation
نویسندگان
چکیده
منابع مشابه
RhoA effector mutants reveal distinct effector pathways for cytoskeletal reorganization, SRF activation and transformation.
The RhoA GTPase regulates diverse cellular processes including cytoskeletal reorganization, transcription and transformation. Although many different potential RhoA effectors have been identified, including two families of protein kinases, their roles in RhoA-regulated events remain unclear. We used a genetic screen to identify mutations at positions 37-42 in the RhoA effector loop that selecti...
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ژورنال
عنوان ژورنال: The EMBO Journal
سال: 1998
ISSN: 1460-2075
DOI: 10.1093/emboj/17.5.1350